Dimethyl Sulfoxide
Medchemexpress LLC HY-Y0320 500mL , Dimethyl sulfoxide CAS:67-68-5 Purity:>98%
HY-Y0320 500mL Dimethyl sulfoxide CAS: 67-68-5 Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves both polar and nonpolar compounds. Dimethyl sulfoxide has anti-freezing and bacteriostatic properties. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Sigma Aldrich Fine Chemicals Biosciences Dimethyl sulfoxide suitabl
Dimethyl sulfoxide (DMSO) is a polar organic solvent. DMSO activated by various electrophiles (oxalyl chloride) has been used to oxidize various alcohols (primary secondary allylic benzylic hindered and bicyclic). Carbonyl compounds are formed as reaction products. Due to its higher stability it has been proposed as an alternate solvent for methyl cellosolve for use in ninhydrin reaction.
Crescent Chemical Co Inc DIMETHYL SULFOXIDE MOL BIO GRD
Dimethyl sulfoxide molecular biology grade DNase/RNase not detected. Size - 50ML Storage Conditions - +15 °C TO +30 °C Catalog Number - 39757.01 CAS 67-68-5
Supply Solutions Dimethyl sulfoxide, 67-68-5, MFCD00002089, 100mL
Linear Formula (CH3)2SO, Molecular Weight 78.13, bp 189 C (lit.), mp 16-19 C (lit.), for molecular biology, Synonym: DMSO
Medchemexpress LLC Dbet6 10Mm 1Md Dmso Reconstit | HY-112588-10MM-DMSO-RECON
Dbet6 10Mm 1Md Dmso Reconstit
Gold Biotechnology Inc Sterile Filtered DMSO
Dimethylsulfoxide (DMSO) is a very polar organic compound that is useful in organic chemistry for solubilizing organic and inorganic compounds DMSO is also used as a cryoprotectant for cell media preventing the formation of ice crystals which would otherwise damage cells DMSO can be used in PCR reactions to inhibit the self-complementation of DNA or PCR primers and increase amplification especially for DNA sequences which have GC rich sequences
Apexbio Technology LLC Pexidartinib (PLX3397) 1029044-16-3 10mM (in 1mL DMSO)
Pexidartinib (PLX3397 CAS 1029044-16-3) is a small molecule inhibitor targeting colony-stimulating factor 1 receptor (CSF-1R) a receptor tyrosine kinase involved in macrophage recruitment and activation Through inhibition of CSF-1R activity this compound reduces macrophage infiltration and accumulation demonstrated by diminished macrophage levels in B16F10 melanoma models without affecting Gr-1 myeloid-derived suppressor cells In vivo studies using GL261 glioma models in C57 mice indicate decreased microglial infiltration upon oral dosing with PLX3397 Clinically combined treatment with Pexidartinib and paclitaxel is under evaluation in advanced solid tumors and breast cancer trials
Apexbio Technology LLC CFTRinh-172 307510-92-5 10mM (in 1mL DMSO)
CFTRinh-172 (CAS 307510-92-5) is a small molecule inhibitor selectively targeting the cystic fibrosis transmembrane conductance regulator (CFTR) a cAMP-activated chloride channel involved in epithelial fluid transport in organs such as lung intestine and pancreas It acts by reversibly and voltage-independently inhibiting CFTR currents with a Ki in the range of 0 3 5 M Experimental studies demonstrate CFTRinh-172 rapidly blocks CFTR-mediated short-circuit currents while exhibiting minimal cross-reactivity towards other channels or transporters In animal models CFTRinh-172 reduces cholera toxin-induced intestinal fluid secretion suggesting potential applications in developing cystic fibrosis models and investigating secretory diarrheal diseases
Apexbio Technology LLC SB 203580 hydrochloride 869185-85-3 10mM (in 1mL DMSO)
SB 203580 hydrochloride (CAS 869185-85-3) is a selective inhibitor targeting the p38 mitogen-activated protein kinases (MAPKs) specifically isoforms p38-MAPK and p38-MAPK It prevents the downstream phosphorylation and activation of MAP kinase-activated protein kinase 2 (MAPKAPK2) exhibiting an IC50 around 70 nM in neonatal myocytes Additionally SB 203580 hydrochloride inhibits MAPKAPK2 activation and heat shock protein 27 (HSP27) phosphorylation induced by IL-1 osmotic stress or arsenite in KB cells with IC50 values below 1 M It also reduces JNK-mediated activation of c-Jun in neonatal rat cardiac myocytes This compound is widely utilized in research into cellular stress responses inflammation pathways and cardiac signal transduction
Apexbio Technology LLC Entinostat (MS-275,SNDX-275) 209783-80-2 10mM (in 1mL DMSO)
Entinostat (MS-275 SNDX-275 CAS 209783-80-2) is an orally bioavailable small molecule inhibitor targeting histone deacetylases (HDACs) a family of enzymes involved in transcriptional regulation by modifying histone acetylation Specifically entinostat exhibits inhibitory activity against class I HDAC enzymes HDAC1 HDAC3 and HDAC8 with reported IC50 values of 0 368 M 0 501 M and 63 4 M respectively In preclinical investigations entinostat demonstrates anti-proliferative effects in diverse human tumor cell lines including breast colon lung multiple myeloma ovarian pancreatic prostate cancers and leukemia Due to these properties entinostat is widely utilized in oncology research